The QSBC is a research hub that uses advanced spatial mapping technology and digital pathology tools to fundamentally change the way clinicians understand and combat life-threatening diseases. QSBC’s research is dedicated to unlocking the secrets of individual cell interactions, leading to personalised treatments for some of our deadliest diseases, including cancer, heart disease and lung disease.

Website

https://www.wesleyresearch.org.au/queensland-spatial-biology-centre/

Organisation type

Not-for-profit

Number of research staff

Up to 20 research staff

Address

Wesley Research Institute Level 8, East Wing, The Wesley Hospital 451 Coronation Drive Auchenflower QLD 4066

Strengths and capabilities

• Translational research
• Spatial tissue mapping
• Spatial phenotyping
• Spatial omics
• Digital pathology
• Cell mapping
• Tissue profiling

Facilities and major equipment

• State-of-the-art spatial omics technology
• Spatial proteomics (high-plex & low-plex technology)
• PC2 laboratory

Lead researchers

• Professor John Fraser has five professorships across major Australian universities, published over 580 peer reviewed publications; and  received more than $41 million in competitive grants.  John is the QSBC Clinical Director, Founder and Director of the Critical Care Research Group, and is also the Director of the Intensive Care Unit at St Andrew’s War Memorial Hospital.
• A/Professor Arutha Kulasinghe has pioneered spatial transcriptomics using digital spatial profiling approaches in the Asia-Pacific region, contributing to world-first studies for lung cancer, head and neck cancer and COVID-19. Dr Kulasinghe has received over $15M in competitive grants and published over 100 peer reviewed publications. Arutha is the QSBC Scientific Director, and leads the Clinical-oMx Lab at the Frazer Institute,

Achievements of the centre

• World-first research project by two Queensland professors is set to offer a blueprint for developing more effective vaccines and therapies and provide insights for influencing global health policies and pandemic response strategies for decades to come.
• The 4 year Lung Cancer METASPATIAL Study will employ advanced spatial omics technology in their effort to revolutionise lung cancer understanding and treatment.
• Latest publications from the QSBC in the field of Spatial biology

Key science sectors

More information about the sectors this centre is involved in:

• Biotechnology
• Digital economy
• Health and medical