Queensland COVID-19 research
This page of Queensland’s research related to the COVID-19 pandemic is compiled from information provided by Queensland universities and research institutes.
While many of our researchers are working on potential vaccines, treatments and other medical interventions, other researchers are applying their expertise to other impacts of the pandemic upon our economy and other aspects of society. The data includes immediate research activity, recent relevant work, proposed research (subject to available funds) and other responses using the resources and expertise of our research organisations.
Listing 3 matching responses out of 149 total responses.
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A systematic review of soap versus sanitiser for preventing the transmission of acute respiratory infections September 2021
Early on in the COVID-19 pandemic researchers from the Institute for Evidence-Based Healthcare undertook a systematic review of randomised trials to compare the effectiveness of hand hygiene using alcohol-based hand sanitiser to soap and water for preventing the transmission of acute respiratory infections, and assess the relationship between the dose of hand hygiene and the number of acute respiratory infections, influenza-like illness, or influenza events. The review concluded that dequately performed hand hygiene, with either soap or sanitiser, reduces the risk of acute respiratory infections virus transmission, however direct and indirect evidence suggest sanitiser might be more effective in practice.
#Treatment#Prevention#Personal Protective Equipment (PPE)#Infection management
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Institute for Evidence-Based Healthcare
Bond University - Contact details
- Prof Tammy Hoffmann
Epidemiologist
thoffmann@bond.edu.au
+617 5595 5522 - Collaborations
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- Co-researchers: Dr Mina Bakhit - Institute for Evidence-Based Healthcare
- Dr Natalia Krzyzaniak - Institute for Evidence-Based Healthcare
- Prof Chris del Mar - Institute for Evidence-Based Healthcare
- Asst Prof Anna Scott - Institute for Evidence-Based Healthcare
- Prof Paul Glasziou - Institute for Evidence-Based Healthcare
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A systematic review and meta-analysis of physical interventions (face masks, eye protection and person distancing) to interrupt or reduce the spread of respiratory viruses September 2021
This systematic Cochrane Review examined the effectiveness of eye protection, face masks, or person distancing on interrupting or reducing the spread of respiratory viruses. This review included a meta-analysis of observational studies during the SARS outbreak of 2003. The study led by the University of Oxford involving seven researchers from Bond Univesity examined randomised and cluster-randomised trials of people of any age, testing the use of eye protection, face masks, or person distancing against standard practice, or a similar physical barrier. Outcomes included any acute respiratory illness and its related consequences. The preprint, still to be peer-reviewed report concluded: Most included trials had poor design, reporting and sparse events. There was insufficient evidence to provide a recommendation on the use of facial barriers without other measures. The researchers found insufficient evidence for a difference between surgical masks and N95 respirators and limited evidence to support effectiveness of quarantine. Based on observational evidence from the previous SARS epidemic included in the previous version of their Cochrane review the researchers recommend the use of masks combined with other measures.
#Treatment#Prevention
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Institute for Evidence-Based Healthcare
Bond University - Contact details
- A/Prof Mark Jones
Biostatistician
majones@bond.edu.au
+61 7 5595 5523
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Decoding the Epigenome in SARS-Cov-2: Novel Avenue for therapeutics for COVID-19 August 2021
People infected with the COVID-19 virus (SARS-CoV-2) who display no viral symptoms (asymptomatic) are capable of being highly contagious as the virus is shed from the upper respiratory tract at unusually high levels at this time. This represent a significant danger of spread of the virus. As the COVID-19 virus persists and is anticipated to cause further disease waves, there is an urgent need for new post-exposure preventative (prophylaxic) drugs or PEPs. Prof Sudha Rao and her team are developing the first-in-class PEP-based drugs and have identified re-purposed drugs in a targeted manner to combat the virus. These inhibitors prevent the virus for entering cells and replicating, thereby reducing the severity of infection and providing time for the person to mount appropriate anti-viral immune responses. They have harnessed their knowledge from drug development in the immuno-oncology field to help combat this pandemic. The team is seeking further funding to undertake critical primate studies to advance this novel class of PEPs to clinical trials.
#Prevention
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Gene Regulation and Translational Medicine Laboratory
QIMR Berghofer Medical Research Institute - Contact details
- Professor Sudha Rao
Group Leader
sudha.rao@qimrberghofer.edu.au
+614 1141 5440 - Collaborations
Other Queensland COVID-19 initiatives
- Queensland Government
- Coronavirus (COVID-19) business assistance finder
- Life Sciences Queensland
- Life Sciences Queensland joins the data-powered alliance to stop COVID-19
Key international COVID-19 initiatives
- CORD-19 (COVID-19 Open Research Dataset)
- Free database of 130,000 plus COVID-19 open research papers